Certain 2-(alpha(2-pyridyl)-benzyl)imidazolines and derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424250, 424251, 424270, 424273R, 424275, 61K 31505, A61K 3145, A61K 31425, A61K 31495

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active

040815447

ABSTRACT:
The present 2-substituted imidazolines and 2-substituted-3,4,5,6-tetrahydropyrimidines possess valuable anti-depressant and anti-inflammatory properties. The compounds are prepared by the condensation of an appropriately substituted nitrile with a diamine. For example, condensation of 2-pyridylbenzyl cyanide with 1,2-ethylene diamine or with 1,3-propylene diamine produces a 2-(2-pyridylbenzyl) imidazoline or a 2-(2-pyridylbenzyl)-3,4,5,6-tetrahydropyrimidine.

REFERENCES:
patent: 2656358 (1953-10-01), Sperber et al.
patent: 3770737 (1973-11-01), Walter
Chem. Abst., vol. 76, Abst No. 59632e, (1972).
Chem. Abst., vol. 55-col 3590 (1961).

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