Certain 2-[.alpha.(2-pyridyl)-benzyl] imidazolines and derivativ

Details Certain 2-[.alpha.(2-pyridyl)-benzyl] imidazolines and derivativ Certain 2-[.alpha.(2-pyridyl)-benzyl] imidazolines and derivativ

1973-11-05

1976-01-13

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, 424251, 424263, 260250R, 2602564H, C07D21344

Patent

active

039324311

ABSTRACT:
The present 2-substituted imidazolines and 2-substituted-3,4,5,6-tetrahydropyrimidines possess valuable anti-depressant and anti-inflammatory properties. The compounds are prepared by the condensation of an appropriately substituted nitrile with a diamine. For example, condensation of 2-pyridylbenzyl cyanide with 1,2-ethylene diamine or with 1,3-propylene diamine produces a 2-(2-pyridylbenzyl) imidazoline or a 2-(2-pyridylbenzyl)-3,4,5,6-tetrahydropyrimidine.

REFERENCES:
patent: 2656358 (1953-10-01), Sperber et al.
patent: 3770737 (1973-11-01), Walter
Chemical Abstracts, Vol. 76, Abst. No. 59632e, (1972).
Chemical Abstracts, Vol. 55, Col. 3590, (1961), (abst. of Carelli et al.).

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