Certain 1H-imidazo[4,5-B]pyrazin-2(3H)-ones and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S350000, C424S451000, C424S464000

Reexamination Certificate

active

07956056

ABSTRACT:
Provided is at least one chemical entity chosen from compounds of Formula I and Formula II:and pharmaceutically acceptable salts thereof, compositions thereof, and methods for their use in modulating one or more of skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, skeletal muscle, and skeletal sarcomere.

REFERENCES:
patent: 3507866 (1970-04-01), Jones et al.
patent: 4195088 (1980-03-01), Barzaghi et al.
patent: 4943573 (1990-07-01), Meanwell
patent: 6162804 (2000-12-01), Bilodeau et al.
patent: 6232320 (2001-05-01), Stewart et al.
patent: 6579882 (2003-06-01), Stewart et al.
patent: 6638933 (2003-10-01), Gerlach et al.
patent: 6657064 (2003-12-01), Gerlach et al.
patent: 7279580 (2007-10-01), Goodacre et al.
patent: 7348339 (2008-03-01), Bailey et al.
patent: 2003/0220365 (2003-11-01), Stewart et al.
patent: 2004/0023972 (2004-02-01), Sundermann et al.
patent: 2004/0166137 (2004-08-01), Lackey
patent: 2005/0197328 (2005-09-01), Bailey et al.
patent: 2005/0250794 (2005-11-01), Napper et al.
patent: 2006/0019952 (2006-01-01), Distefano et al.
patent: 2006/0148805 (2006-07-01), Chen et al.
patent: 2007/0197507 (2007-08-01), Morgan et al.
patent: 2007/0275984 (2007-11-01), Imogai et al.
patent: 2008/0096903 (2008-04-01), Chen et al.
patent: 2008/0146561 (2008-06-01), Muci et al.
patent: 2008/0024695 (2008-10-01), Morgan et al.
patent: 2009/0023724 (2009-01-01), Mortensen et al.
patent: 2009/0082370 (2009-03-01), Thompson et al.
patent: 2009/0247538 (2009-10-01), Berdini et al.
patent: 2010/0022564 (2010-01-01), Davies et al.
patent: 2241575 (1973-03-01), None
patent: 2 174 987 (1986-11-01), None
patent: 2 190 676 (1987-11-01), None
patent: 2 400 101 (2004-10-01), None
patent: 40080 (1975-12-01), None
patent: WO 99/62908 (1999-12-01), None
patent: WO 2005/002520 (2005-01-01), None
patent: WO 2005/060711 (2005-07-01), None
patent: WO 2005/072412 (2005-08-01), None
patent: WO 2005/108374 (2005-11-01), None
patent: WO 2006/030031 (2006-03-01), None
patent: WO 2006/036883 (2006-04-01), None
patent: WO 2006/046024 (2006-05-01), None
patent: WO 2007/125310 (2007-11-01), None
patent: WO 2007/125321 (2007-11-01), None
patent: WO 2008/016648 (2008-02-01), None
patent: WO 2008/049105 (2008-04-01), None
patent: WO/2008/051493 (2008-05-01), None
patent: WO 2008/089459 (2008-07-01), None
International Search Report and Written Opinion mailed Jul. 1, 2008 for PCT/US2008/004075.
International Search Report and Written Opinion mailed Aug. 8, 2008 for PCT/US2007/017191.
International Search Report and Written Opinion mailed Oct. 1, 2008 for PCT/US2007/017235.
Office Action mailed Oct. 21, 2008 for U.S. App. No. 11/888,902, filed Aug. 1, 2007.
Jordan, Nature Reviews, Drug Discovery 2:205-213 (Mar. 2003).
Dörwald, Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design, Weinheim: Wiley-VCH Verlag GmbH & Co., KGaA, Preface (2005).
Barlin, Aust. J. Chem., 35:2299-2306 (1982).
International Search Report and Written Opinion mailed Apr. 8, 2009 for PCT/US2009/000686.
Office Action mailed Mar. 5, 2009 for U.S. Appl. No. 11/888,902, filed Aug. 1, 2007.
Lima et al., Current Medicinal Chemistry 12(1):23-49 (2005).
Notice of Allowance for U.S. Appl. No. 11/888,902, mailed Jun. 1, 2009.
Bianchi, Mario, “Compounds with antiulcer and antisecretory activity,III. N-substituted imidazolones condensed with nitrogen-containing heteroaromatic rings”,European Journal of Medicinal Chemistry, 18(6):501-506 (1983).
Bjoerk, Malin et al., “Synthesis of novel 2-aminoimidazo [4,5-b] pyridines, including the thieno analogue of the cooked-food mutagen IFP”,Journal of Heterocyclic Chemistry, 43(1) :101-109 (2006).
Lindström, Stefan et al., “Synthesis of the Mutagenic 2-Amino-1,6-Dimethyl-Imidazo[4,5-b]Pyridine (1,6-DMIP) and Five of Its Isomers”,Heterocycles, Elsevier Science Publishers B.V. 38(3):529-540 (1994).
Meanwell, Nicholas A, et al., “Inhibitors of blood platelet cAMP phosphodiesterase.2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains”,Journal of Medicinal Chemistry, 35(14):2672-87 (1992).
Meanwell, Nicholas A. et al., “Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility”,Journal of Medicinal Chemistry, 35(14): 2688-96 (1992).
Meanwell, Nicholas A. et al., “1,3 Dihydro-2H-imidazo[4,5-b]quinolin-2-ones—Inhibitors of Blood Platelet cAMP Phosphodiesterase and Induced Aggregation”,Journal of Medicinal Chemistry, 34(9):2906-16 (1991).
Yutilov, Yu. M. et al., “Halogenation of Imidazo[4,5-b]pyridin-2-one Derivatives”,Russian Journal of Organic Chemistry, 41(4):575-579 (2005).
Yutilov, Yu. M. et al., “Halogenation of 2-Unsubstituted and 2-Methylinnidazo[4,5-b]pyridine Derivatives”,Russian Journal of Organic Chemistry, 41(3):450-454 (2005).
Supplementary European Search Report mailed Apr. 8, 2010, for PCT/US2008/004075.
Office Action mailed Feb. 25, 2010 for U.S. Appl. No. 12/058,127, filed Mar. 28, 2008.
Notice of Allowance mailed Aug. 9, 2010 for U.S. Appl. No. 12/058,127, filed Mar. 28, 2008.

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