Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecar

Details Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecar Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecar

1984-08-27

1987-05-12

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548202, 546342, C07D23358

Patent

active

046651888

ABSTRACT:
Benzocycloalkane derivatives of the formula (I) ##STR1## wherein: Z represents a methylene group or an ethylene group, either one of R.sup.1 and R.sup.2 represents --(CH.sub.2).sub.m --COOR.sup.3 and the other represents ##STR2## wherein R.sup.3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, n represents an interger of 1 to 6 and m represents an interger of 0 to 5, and the physiologically acceptable salts thereof; having a strong and selective inhibition activity of thromboxane A.sub.2 synthesis.

REFERENCES:
patent: 4496572 (1985-01-01), Cross et al.
patent: 4510149 (1985-04-01), Cozzi et al.

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