Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1975-05-28
1977-04-12
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2602471H, 2602471M, 2602472A, 260268H, 26029369, 2602948F, 2602949, 2602955R, 424267, A61K 31455, C07D21186
Patent
active
040176290
ABSTRACT:
The present invention relates to 1,4-dihydropyridines of the formula I ##STR1## and their tautomers, wherein R.sub.1 represents an aryl radical, R.sub.2 and R.sub.3 independently of one another represents hydrogen or a hydrocarbon radical, R.sub.4 represents an alkyl, aryl or aralkyl radical, R.sub.5 denotes an alkoxy radical, which is optionally substituted by an amino group, or denotes an amino group and n is 1 or 2, especially to the 2,6-dimethyl-3-carbomethoxy-5-methylsulphonyl-4-(2-trifluoromethylphenyl)- 1,4-dihydro-pyridine and to the 2,6-dimethyl-3-carbomethoxy-5-methylsulphonyl-4-(2-nitrophenyl)-1,4-dihydr opyridine.
They have an antihypertensive activity.
REFERENCES:
patent: 3867393 (1975-02-01), Meyer et al.
patent: 3883540 (1975-05-01), Meyer et al.
Habicht Ernst
Kuhnis Hans
Ciba-Geigy Corporation
Groeger Theodore O.
Kolodny Joseph G.
Maitner John J.
Rotman Alan L.
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