Cerebral protecting agent

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540575, 544378, 514254, C07D40504

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active

048268402

ABSTRACT:
An indene compound of the general formula (I): ##STR1## in which R.sub.1 represents a lower alkyl group, R.sub.2 represents a hydrogen atom, an aryl group or lower alkyl group, R.sub.3 represents an alkyl group, and n indicates an integer of 2 or 3; or a salt thereof. The compound has very strong ameliorating or improving effects on cerebral circulation and metabolism, and thus is very useful for ameliorating, or suppressing the progress of, disturbances of brain tissues and functions.

REFERENCES:
patent: 4393226 (1983-07-01), Witiak et al.
patent: 4443448 (1984-04-01), Bogeso
Journal of Medicinal Chemistry, 21, No. 12, pp. 1313-1315, 1978.

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