Cephem compounds and their production

Details Cephem compounds and their production Cephem compounds and their production

1984-12-14

1987-05-19

Hendricks, Glenna M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540230, 514201, 514209, 530331, A61K 31545, C07D50140

Patent

active

046670270

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 stands for hydrogen or formylamino, R.sup.2 is a residue of amino acid selected from the group consisting of serine and alanine, or a peptide of at least one of these amino acids, or hydrogen, R.sup.3 stands for --NH--C(.dbd.NH)--NH.sub.2 or --CH.sub.2 NH.sub.2, or its salt, which can be produced by cultivating a microorganism belonging to the genus Xanthomonas, is useful as a therapeutic agent against infectious disease caused by bacteria.

REFERENCES:
Hamilton--Miller, et al., "Products of Aninolysis . . . of Cephalosporins", Biochem. J. (1970), 116, 371-381.
The Journal of Antibiotics, vol. 37, No. 7, pp. 773-780, (1984).
Program and Abstracts of the Twenty--Fourth Interscience Conference on Antimicrobial Agents and Chemotherapy, p. 292, (1984), No. 1139.

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