Cepham derivatives

Details Cepham derivatives Cepham derivatives

1989-12-27

1991-02-19

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540230, 540221, C07D50118, A61K 31545

Patent

active

049944541

ABSTRACT:
A process is provided for the preparation of 3-methylene and 3-halomethylene cepham derivatives via 3-phosphoniomethyl-3-cephem derivatives, which in turn can be prepared from 3-halomethyl-3-cephem derivatives. The preparation can be carried out with or without isolating the intermediate phosphonium cephem compounds. The 3-methylene and 3-halomethylene cephem derivatives and in particular the 1-oxo and 1,1-dioxo cephem compounds are also prepared by reducing a 3-halomethyl-3-cephem derivative with activated metal, preferably zinc or magnesium.

REFERENCES:
patent: 4731443 (1988-03-01), Takaya et al.

Affiliated with

Also associated with

Rating

Cepham derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cepham derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cepham derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1143780