Harness for working animal
Patent
1981-05-04
1983-05-31
Coughlan, Jr., Paul M.
Harness for working animal
544 21, 544 25, 544 27, 544 28, C07D50156
Patent
active
043861997
ABSTRACT:
Cephalosporins of the formula ##STR1## wherein R is hydrogen, sodium, potassium, or certain ester groups; R.sub.1 is in the .alpha.-configuration and is hydrogen or methoxy; R.sub.2 is hydrogen, lower alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl, furyl, or pyridyl, or 2-amino-4-thiazolyl; R.sub.3 is lower alkyl or substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl, or furyl; R.sub.4 is hydrogen or lower alkyl; and X is hydrogen, ##STR2## --O--lower alkyl, or certain substituted or unsubstituted heterothio groups; are disclosed. These compounds possess useful antibacterial activity.
REFERENCES:
patent: 4147693 (1979-04-01), Konig et al.
patent: 4182762 (1980-01-01), Preiss
patent: 4200576 (1980-04-01), Feyen et al.
Burger, Medicinal Chemistry, 3rd Ed., (1970), pub. by Wiley-Interscience, p. 391.
Breuer Hermann
Treuner Uwe D.
Coughlan, Jr. Paul M.
Davis Stephen B.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
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