Cephalosporins having an .alpha.-acyloxyacetic acid side chain

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260250A, 260287H, 260295R, 260308R, 544 27, A61K 31545, C07D50136

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active

040679799

ABSTRACT:
The invention relates to compounds of the formula ##STR1## wherein R.sub.1 denotes optionally substituted phenyl, thienyl, furyl or 1,4-cyclohexadienyl, R.sub.2 represents a free carboxyl group or an esterified carboxyl group which can be split physiologically, R.sub.3 represents hydrogen, lower alkoxy or an optionally substituted methyl group, and B represents a monosubstituted or polysubstituted six-membered ring with 1 to 3 ring nitrogen atoms which is bonded to the carbonyl group --C(.dbd.O)-- by one of its ring carbon atoms, and the salts of such compounds which have salt-forming groups, which compounds possess antibiotic properties.

REFERENCES:
patent: 3812116 (1974-05-01), Takano et al.
patent: 4000133 (1976-12-01), Kariyone et al.
patent: 4006138 (1977-02-01), Yang

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