Cephalosporins

Details Cephalosporins Cephalosporins

1980-10-14

1983-04-12

Rizzo, Nicholas S.

Harness for working animal

544 21, 424246, C07D50157, A61K 31545

Patent

active

043799205

ABSTRACT:
Cephamycin compounds of the formula (I) ##STR1## wherein R.sup.1 represents hydroxyl or sulphooxy and R.sup.2 represents sulphooxy together with derivatives thereof including salts, esters, N-protected derivatives and solvates thereof are disclosed. These compounds are of great value as intermediates in the preparation of other cephamycin compounds.
The compounds of the invention may be isolated from fermentation broths of strains of the genus Streptomyces which produce the compounds and a new such strain is described. The isolation of the compounds may be achieved by a liquid/liquid or liquid/solid ion-exchange technique, and is preferably achieved by the formation of an ion-pair in a liquid/liquid technique.

REFERENCES:
patent: 3914157 (1975-10-01), Stapley et al.
patent: 4017485 (1977-04-01), Hasegawa et al.
patent: 4103083 (1978-07-01), Ogawa et al.
patent: 4259326 (1981-03-01), Gushima et al.
patent: 4302578 (1981-11-01), Stapley et al.

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