Cephalosporins

Details Cephalosporins Cephalosporins

1988-10-31

1991-12-24

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540222, 540225, C07D50124, A61K 31545

Patent

active

050752987

ABSTRACT:
A compound selected from the group consisting of a syn isomer of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl and alkynyl of 2 to 6 carbon atoms and cycloalkyl of 3 to 6 carbon atoms, all optionally substituted with at least one member of the group consisting of optionally esterified or salified carboxy, alkoxy carbonyl, carbamoyl, dimethylcarbamoyl, amino, alkylamino, dialkylamino, halogen, alkoxy and alkylthio of 1 to 4 carbon atoms, aryl, heterocyclic aryl, arylthio and heterocyclic arylthio optionally substituted by alkyl of 1 to 4 carbon atoms, R.sub.1 is selected from the group consisting of ##STR2## and A is selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, magnesium, --NH.sub.4 and an organic amine or A is selected from the group consisting of the residue of an easily cleavable ester group or --COOA is --COO-- and the wavy line indicates --CH.sub.2 --R.sub.1 is in the E or Z position and their non-toxic, pharmaceutically acceptable acid addition salts having good antibacterial activity.

REFERENCES:
Chemical Abstracts vol. 112, 118535(m) (1990).
Chemical Abstracts vol. 111, 194449(g) (1989).

Affiliated with

Also associated with

Rating

Cephalosporins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cephalosporins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cephalosporins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-43564