Cephalosporins

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544 22, 544 25, 544 27, 544 28, C07D50134, C07D50136, C07D50146, C07D50156

Patent

active

041728912

ABSTRACT:
A novel cephalosporin derivative of the formula: ##STR1## [wherein X is hydrogen, hydroxyl, acyloxy, alkoxy, carbamoyloxy, quaternary ammonium or a group of the formula --SR.sup.1 (where R.sup.1 is a nitrogen-containing heterocyclic group)] or a pharmaceutically acceptable salt or ester thereof is found to have potent antibiotic activity against various bacteria, particularly against gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri and Citrobacter freundii.

REFERENCES:
patent: 2500131 (1950-03-01), Linsker
patent: 2518130 (1950-08-01), Evans et al.
patent: 4008246 (1977-02-01), Ochiai et al.

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