Cephalosporin type antibacterials

Details Cephalosporin type antibacterials Cephalosporin type antibacterials

1976-06-28

1979-02-13

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 26, 544 27, C07D50136

Patent

active

041396189

ABSTRACT:
3-[3-(methyl-1,3,4-thiadiazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha.-s ubstituted acetamido)-ceph-3-em-4-carboxylic acids; 3-[3-(3-methyl-1,2,4-thiadiazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha .-substituted acetamido)-ceph-3-em-4-carboxylic acids; and 3-[3-(2-methyl-1,3,4-oxadiazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha. -substituted acetamido)-ceph-3-em-4-carboxylic acids and derivatives and salts thereof and processes for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.

REFERENCES:
patent: 3516997 (1970-06-23), Takano et al.
patent: 3983113 (1976-09-01), Beeby
patent: 4013650 (1977-03-01), Fechtig
patent: 4016159 (1977-04-01), Bormann et al.

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