Cephalosporin hydroxamic acids

Details Cephalosporin hydroxamic acids Cephalosporin hydroxamic acids

1984-02-02

1986-09-30

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540221, 540227, 514201, 514204, 514206, C07D50136, A61K 31545

Patent

active

046147977

ABSTRACT:
An antibacterial cephalosporin hydroxamic acid derivative represented by the following formula (I), processes for its preparation, compositions containing the same as an active ingredient, and a method for killing bacteria by contacting with said compound. ##STR1## (wherein, R is acyl; R.sup.1 is hydrogen or methoxy; R.sup.2 is alkylene; R.sup.3 is hydrogen, aliphatic group or a hydroxy-protecting group; R.sup.4 is hydrogen or amino-protecting group; R.sup.5 is hydrogen, light metal atom or carboxy-protecting group; and X is oxygen, sulfur, or sulfinyl).

REFERENCES:
patent: 4066761 (1978-01-01), Berges
patent: 4068073 (1978-01-01), Berges
patent: 4286089 (1981-08-01), Berges

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