Cephalosporin derivatives, their preparation and compositions co

Details Cephalosporin derivatives, their preparation and compositions co Cephalosporin derivatives, their preparation and compositions co

1983-08-11

1985-04-02

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 25, 544 24, A61K 31545, C07D50136

Patent

active

045087172

ABSTRACT:
Cephalosporin derivatives of the formula: ##STR1## in which A is a single bond or a radical --CH.sub.2 --, --NH-- or --NHCO--, attached to the 3-position or 4-position of the pyridinio radical, R is a methyl, carboxymethyl, carbamoylmethyl, benzyl or allyl radical, R.sub.a, R.sub.b and R.sub.c are hydrogen atoms, or alternatively R.sub.a is carboxyl and R.sub.b and R.sub.c, which are identical or different, are hydrogen atoms or alkyl radicals, or together form an alkylene radical, and n equals 0 or 1, in their syn form, and also their addition salts with acids, metal salts and addition salts with nitrogen-containing bases are antibacterial agents having a broad spectrum of activity.

REFERENCES:
patent: 4258040 (1981-03-01), Christensen et al.
patent: 4470983 (1984-09-01), Blumbach et al.
Chem. Abst. vol. 81, 1974, Cristensen, 49691n.

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