Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-09-19
1991-09-17
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514201, 540221, 540222, 540225, C07D50118, F61C 31545
Patent
active
050495585
ABSTRACT:
A cephalosporin derivative of the formula I: ##STR1## in which X is ##STR2## represents one of C-7 acyl groups known in the cephalosporin art, R3 is hydrogen or methoxy, R4 is hydrogen, optionally substituted alkyl or allyl, and R5 is an aromatic heterocyclic ring system which is linked via carbon, and which contains a quaternized nitrogen atom.
REFERENCES:
patent: 4489072 (1984-12-01), Sadaki et al.
patent: 4500526 (1989-02-01), Imae et al.
patent: 4678781 (1987-07-01), Jung
J. Med. Chem., 1975, 17, 1312-1315 (Nomura et al.).
Bradbury Robert H.
Jung Frederic H.
Lohmann Jean J.
Marsham Peter R.
Pasquet Georges
ICI Pharma
Imperial Chemical Industries plc
Rizzo Nicholas S.
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