Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-08-27
1998-09-08
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514206, 514225, 540221, 540222, 540227, 540225, A61K 31545, C07D50134
Patent
active
058045775
ABSTRACT:
The present invention relates to compounds of formula I ##STR1## wherein R.sup.1 is a group selected from 2-, 3-, and 4-hydroxyphenyl, 3-nitrophenyl, and 3-fluoro-4-hydroxyphenyl; as well as readily hydroyzable esters thereof, pharmaceutically acceptable salts of said compounds and hydrates of the compounds of formula I and of their esters and salts.
REFERENCES:
patent: 4255423 (1981-03-01), Beattie et al.
patent: 5523400 (1996-06-01), Wei et al.
Heinze-Krauss, I., et al., Journal of Medicinal Chemistry, 39(9):1864-71 (1996).
Hebeisen Paul
Heinze-Krauss Ingrid
Richter Hans
Runtz Valeri
Stalder Henri
Hoffmann-La Roche Inc.
Johnston George W.
Kass Alan P.
Shah Mukund J.
Sripada Pavanaram K.
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