Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1977-12-23
1983-04-12
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
424246, C07D50136, A61K 31545
Patent
active
043799248
ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 represents hydrogen or an alkyl group, X represents oxygen or sulfur or a group of formula --NR.sup.2 (where R.sup.2 is hydrogen or an alkyl group and in the case of alkyl, it may form a ring jointed with R.sup.1), and Y represents acetoxy group or a group of formula --SR.sup.3 (where R.sup.3 is a nitrogen-containing heterocyclic group), or a pharmaceutically acceptable salt thereof, is found to have a broad antimicrobial spectrum and, in particular, effective against gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus morganii, as well as gram positive ones. Thus, these compounds may be used for antimicrobial agents in therapeutical purposes.
REFERENCES:
patent: 3516997 (1970-06-01), Takano et al.
patent: 3926984 (1975-12-01), Teller et al.
patent: 4077965 (1978-03-01), Kamiya et al.
patent: 4080498 (1978-03-01), Numata et al.
Mimamida Isao
Miyawaki Toshio
Numata Mitsuo
Shiraishi Mitsura
Yamaoka Masayoshi
Rizzo Nicholas S.
Takeda Chemical Industries Ltd.
LandOfFree
Cephalosporin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cephalosporin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cephalosporin derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-939544