Cephalosporin derivatives

Details Cephalosporin derivatives Cephalosporin derivatives

1986-10-17

1988-06-14

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540225, C07D50146, A61K 31545

Patent

active

047512954

ABSTRACT:
7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(substituted)-iminoacetamido]-3-[3-( quaternaryammonio)-1-propen-1-yl]-3-cephem-4-carboxylates of the formula ##STR1## in which R.sup.1 and R.sup.2 are defined herein and --.sup..sym. N.tbd.Q is a quaternary ammonio group as defined herein, and salts, solvates, hydrates and esters thereof, are potent antibacterial agents. Processes for their preparation and intermediates in such processes are described.

REFERENCES:
patent: 4381299 (1983-04-01), Terajii et al.
patent: 4486586 (1984-12-01), Narita et al.

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