Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-09-16
1984-05-01
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544 28, A61K 31545, C07D50134
Patent
active
044461372
ABSTRACT:
A compound having the general formula (I) is derived from a cephalosporin; ##STR1## wherein R' is a hydrogen atom, an alkyl group having 1 to 4 atoms or an alkali metal and R is --CH.sub.2 COOR', --CH.sub.2 CH.sub.2 SR', ##STR2## or --CH.sub.2 CH.sub.2 COOR' wherein R' is defined above. A pharmaceutical composition containing the compound is excellent in an antibacterial activity, the activity being recovered by the action of an activating enzyme in a living body although the compound per se shows a low activity against the beneficial bacterial colonies in a living body.
REFERENCES:
patent: 3635953 (1972-01-01), Wolf et al.
patent: 3641015 (1972-02-01), Lewis et al.
Ando Takao
Fujii Masahiko
Furusho Takao
Muto Shigeaki
Niimura Kouichi
Coughlan, Jr. Paul M.
Kureha Kagaku Kogyo Kabushiki Kaisha
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