Cephalosporin compounds

Details Cephalosporin compounds Cephalosporin compounds

1994-12-19

1996-04-02

Rizzo, Nicholas

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540225, C07D50157, A61K 31545

Patent

active

055040764

ABSTRACT:
7.beta.- 2-(aminothiazolyl and thiadiazolyl)-2-oxyiminoacetamido!cephalosporin derivatives having a 3- N-(optionally substituted) aminopyridiniumthiomethyl! substituent have antibacterial activity and are of use in antibacterial therapy. Processes for the preparation of such cephalosporins plus intermediates for use in the preparation thereof, including N-(optionally substituted)amino-thiopyridones, are also described.

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patent: 4971963 (1990-11-01), Sendai et al.
patent: 5008260 (1991-04-01), Yamauchi et al.
patent: 5173485 (1992-12-01), Sakane et al.
patent: 5275816 (1994-01-01), Branch et al.
patent: 5336673 (1994-08-01), Man et al.
Journal of Heterocyclic Chemistry, vol. 11, No. 4, Aug. 1974, Action of Amines and Carbonyl Reagents on 3,5-Diphenyl-4-pyrone and its Thio . . . pp. 487-490.
Bulletin of the chemical Society of Japan, vol. 51, 1978, Reactions of 4H-Pyran-4-thiones with Ammonia, Hydrazine and Guanidine, pp. 179-181.
Journal of the Chemical Society, 1977, Preparation of NN'-Linked Bi(heteroaryls) from Dehydroacetic Acid and 2, 6-Dimethyl-4-pyrone, pp. 1428-1436.

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