Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-07-12
1976-04-06
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424246, C07D50118
Patent
active
039489060
ABSTRACT:
7.beta.-Amino- and acylamidoceph-3-em-4-carboxylic acids having at the 3-position a halo-, formyloxy-, isothiocyanato- or haloacetoxymethyl group and salts and esters thereof. These compounds are useful as starting compounds for preparing 7.alpha.-acylamidoceph-3-em-4-carboxylic acids having a group at the 3-position, other than 3-acetoxymethyl, by reaction with a nucleophile. The compounds prepared have modified antibiotic activity.
REFERENCES:
patent: 3766177 (1973-10-01), Webber et al.
Eardley Stephen
Kennedy James
Long Alan Gibson
Glaxo Laboratories Limited
Rizzo Nicholas S.
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