Cephalosporin C acylase

Details Cephalosporin C acylase Cephalosporin C acylase

1993-02-19

1994-08-09

Baker, Keith

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 691, 435 49, 435 51, 4351723, 4352523, 4353201, 536 232, 935 14, C12N 980, C12N 1552

Patent

active

053366131

ABSTRACT:
The present invention concerns a mutant cephalosporin C acylase derived from a precursor of the formula:

REFERENCES:
patent: 4752585 (1988-06-01), Koths et al.
patent: 4835260 (1989-05-01), Shoemaker
patent: 4959314 (1990-09-01), Mark et al.
patent: 5192678 (1993-03-01), Iwami et al.
Bowie et al. (1990) Science 247, 1306-1310.
Ichiro Aramori et al, "Cloning and Nucleotide Sequencing of New Glutaryl 7-ACA and Cephalosporin C Acylase Genes from Pseudomonas Strains," Journal of Fermentation and Bioengineering, vol. 72, No. 4, (1991), pp. 232-243.
Ichiro Aramori et al, "Isolation of Soil Strains Producing New Cephalosporin Acylases," Journal of Fermentation and Bioengineering, vol. 72, No. 4, (1991), pp. 227-231.

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