Cephalosporin antibiotics

Details Cephalosporin antibiotics Cephalosporin antibiotics

1971-02-16

1981-11-24

Rizzo, Nicholas S.

Harness for working animal

544 21, 424246, C07D50120

Patent

active

043025781

ABSTRACT:
Disclosed are 7.beta.-(D-5-amino-5-carboxyvaleramido)-7-methoxy-3-cephem-4-carboxylic acids which are substituted in the three position of the "cephem" nucleus by a variety of alkyl, haloalkyl or oxygen, sulfur and nitrogen containing substituents; and the salts, esters and amide derivatives thereof. Certain of the products are obtained by fermentation and others are obtained by synthetic means. The products exhibit activity against gram-negative and gram-positive bacteria.

REFERENCES:
Nagarajan, JACS, 93:9, May 5, 1971, pp. 2308-2312.

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