Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-06-29
1985-12-24
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544 22, A61K 31545, C07D50124
Patent
active
045606838
ABSTRACT:
Cephalosporin antibiotics of general formula ##STR1## (wherein R.sup.1 represents a hydrogen atom or a methyl or 2-chloroethyl group) and non-toxic salts and non-toxic metabolically labile esters thereof. The compounds exhibit broad spectrum antibiotic activity and have high activity against both Gram-positive and Gram-negative organisms, including many .beta.-lactamase producing strains. Processes for the preparation of the compounds and pharmaceutical compositions containing them are described.
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Morrison and Boyd, "Organic Chemistry", 3rd Ed., pp. 673, 675, 746 & 747.
Benson Robert
Daus Donald G.
Glaxo Group Limited
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