Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1980-09-09
1982-05-11
Coughlan, Jr., Paul M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
424246, C07D50146
Patent
active
043294537
ABSTRACT:
(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)acetamid o]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate in the form of its crystalline pentahydrate. This pentahydrate has a well defined crystalline structure and exhibits good stability on storage. The pentahydrate exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with .beta.-lactam antibiotics.
REFERENCES:
patent: 4258041 (1981-03-01), O'Callaghan et al.
Brodie Alastair C.
Wetherill Lewis A.
Coughlan, Jr. Paul M.
Glaxo Group Limited
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