Cephalosporin antibacterial compounds

Details Cephalosporin antibacterial compounds Cephalosporin antibacterial compounds

1990-06-20

1992-11-10

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540221, 540222, 540226, 540228, C07D50116, A61K 31545

Patent

active

051625237

ABSTRACT:
Antibacterial compounds of the formula ##STR1## in which R.sub.1 is a cyclic or secondary acyclic amino group which independently has antibacterial activity;

REFERENCES:
patent: Re32491 (1987-09-01), Iwanami et al.
patent: 3971778 (1976-07-01), Cook et al.
patent: 4152432 (1979-05-01), Heymes et al.
patent: 4187221 (1980-02-01), Micetich et al.
patent: 4202893 (1980-05-01), Haynes et al.
patent: 4229443 (1980-10-01), Binderup
patent: 4259333 (1981-03-01), Binderup
patent: 4263432 (1981-04-01), Iwanami et al.
patent: 4278792 (1981-07-01), Cesti et al.
patent: 4404373 (1983-09-01), Iwanami et al.
patent: 4431653 (1984-02-01), Wei et al.
patent: 4476123 (1984-10-01), Labeeuw et al.
patent: 4604387 (1986-08-01), Labeeuw et al.
patent: 4647556 (1987-03-01), Lattrell et al.
patent: 4670444 (1987-06-01), Grohe et al.
patent: 4753925 (1988-06-01), Grohe et al.
patent: 4753953 (1988-06-01), Masuzawa et al.
patent: 4758567 (1988-06-01), Desideri et al.
patent: 4762831 (1988-08-01), Grohe et al.
patent: 4762845 (1988-08-01), Chu et al.
patent: 4767762 (1988-08-01), Chu
patent: 4808711 (1989-02-01), Shimizu et al.
patent: 4844902 (1989-07-01), Grohe
patent: 4946837 (1990-08-01), Miyoke et al.
patent: 4946847 (1990-08-01), Jolidon et al.
Chemical Abstracts vol. 97 55572 (1982).
Chemical Abstracts vol. 98 125757 (1982).
"Burger's Medicinal Chemistry," Wolff, M. E., ed., Fourth Ed., Part II, pp. 83-85, 100-101, 107-108, 131-136.
Agnew. Chem. Int. Ed. Engl., 24, 180 (1985).
"Beta-Lactam Antibiotics for Clinical Use," Queener et al eds.; Marcel Dekker, Inc., New York (1986) pp. 3-49; 268-269.
"Cephalosporin and Penicillins--Chemistry and Biology," Flynn ed., Academic Press, New York (1972), pp. 496-582.
Lund, F. J. "6-Amidinopenicillanic Acids--Synthesis and Antibacterial Properties", Leo Pharmaceutical Products--Recent Advances in the Chemistry of Lactam Antibiotics, pp. 25-27 (England 1977).
Albrecht et al, Derwent 88-001255/01 (1988).
Albrecht et al, Derwent 89-194159/27 (1989).
O'Callaghan et al., Antimicrobial Agents and Chemotherapy, 10(2), 245 (1976).
O'Callaghan et al., J. Bacteriology, 110(3), 988 (1972).
Mobashery et al., J. Amer. Chem. Soc., 108, 1685 (1986).
Mobashery et al,. J. Bio. Chem., 261(17), 7879 (1986).
Russell et al., J. Bacteriology, 106(1), 65 (1971).
Decad et al., J. Bacteriology, 128(1), 325 (1976).
Nikaido, "The Role of Outer Membrane Permeability in the Sensitivity and Resistance of Gram-Negative Organisms to Antibiotics," in Drug Resistance in Bacteria, S. Mitsuhnshi (ed.), Thiene-Shetton Inc., NY (1982), 317-324.
Faraci et al., J. Amer. Chem. Soc., 106, 1489 (1989).
Jeffery et al., J. Org. Chem., 47(3), 587 (1982).
Litter, "Farmacologia," 6a. Ed. El Ateneo, Buenos Aires (1980), p. 1517.
Albrecht et al., J. Med. Chem., 33, 77 (1990).
Albrecht et al., J. Med. Chem. 34, 669 (1991).
Albrecht et al., J. Med. Chem., 34, 2857 (1991).
Biochem. J., 116, 371 (1970).
Antimicrobial Agents and Chemotherapy, 10(2), 245 (1976).
Progress in Drug Research, 21, 9, 9 (1977).
The Chemistry and Biology of .beta.-Lactam Antibiotics, vol. 3, App. A pp. 379-392 (1982).
Antimicrobial Agents and Chemotherapy, 28(4), 581 (1985).
Annual Reports in Medicinal Chemistry, 20, 145 (1985).
J. Med. Chem., 29(3), 394 (1986).
Annual Reports in Medicinal Chemistry, 21, 139 (1986).
Antimicrobial Agents and Chemotherapy, 31(4), 614 (1987).
American Journal of Medicine, 82, (Supp. 4A), 12 (Apr. 27, 1989).
J. Antimicrobial Chemotherapy, 17, 5 (1986).
Annual Reports in Medicinal Chemistry, 21, 117 (1987).
Antimicrobial Agents and Chemotherapy, 31(11) 1831 (1987).
Drugs, 34 (Supp. 2), 1 (1987).
J. Med. Chem., 31, 983 (1988).
J. Med. Chem., 31, 991 (1988).
Hackh's Chemical Dictionary, Grant J., ed., 3rd Ed., McGraw-Hill, New York, p. 814 (1944).
Antimicrobial Agents and Chemotherapy, 10(2), 249 (1976).
J. Med. Chem., 5, 1063 (1962).
J. Med. Chem., 20(6), 791 (1977).
J. Med. Chem., 21(5), 485 (1978).
J. Med. Chem., 23(12), 1358 (1977).
J. Med. Chem., 27(3), 292 (1984).
J. Med. Chem., 27(9), 1103 (1984).
J. Med. Chem., 27(12), 1543 (1984).
J. Med. Chem., 28(11), 1558 (1985).
J. Med. Chem., 29(3), 394 (1986).
J. Med. Chem., 29(4), 445 (1986).
J. Med. Chem., 30(3), 504 (1987).
Tetrahedron, 23, 4719 (1967).
Synthesis, 787 (1979).
J. Heterocyclic Chem., 22, 1033 (1985).
Derwent Abstract of EPA 060,745.
Derwent Abstract of EPA 178,980.
Heifetz, Carl L. and Domagala, John M., "The New Generation of Quinolones", Marcel Dekker, Inc., New York, 1990.

Affiliated with

Also associated with

Rating

Cephalosporin antibacterial compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cephalosporin antibacterial compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cephalosporin antibacterial compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2294982