Cephalosporin analogues and compositions

Details Cephalosporin analogues and compositions Cephalosporin analogues and compositions

1977-02-07

1978-08-22

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424854, 544 90, A01N 900, A01N 922, C07D26500, C07D27300

Patent

active

041089928

ABSTRACT:
Novel cephalosporin analogues, salts and esters thereof, their preparation, intermediates and antibacterial compositions containing them. The compositions are formulated for human use into unit dosage form containing 100-4,000 mg of antibacterial compound. The cephem analogues are characterized by having a ring O-heteroatom instead of a ring N-heteroatom and are designated as oxacephems.

REFERENCES:
patent: 3728342 (1973-04-01), Kukolja
patent: 3769277 (1973-10-01), Long et al.
patent: 3795672 (1974-03-01), Murphy
patent: 4011216 (1977-03-01), Menard et al.
patent: 4013648 (1977-03-01), Horning et al.
patent: 4013653 (1977-03-01), Wolfe
J. Heterocyclic Chem. 5, 779-783, 1968-Sheehan et al., "The Synthesis of Oxygen Analogs of Cepham".

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