Cephalosporin analogues

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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544 90, C07D20500

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active

041430387

ABSTRACT:
Potent antibacterial cephalosporin analogues of the following formula in forms of free acids, pharmaceutically acceptable salts, or esters preparable from penicillins through azetidinone derivatives by way of a new process, and utilizable as active ingredients in bactericidal compositions for pharmaceutical and veterinary use: ##STR1## (wherein Acyl is selected from phenylacetyl, D-mandeloyl, .alpha.-phenylmalonyl, D-.alpha.-(3-methanesulfonyl-2-oxoimidazolidin-l-yl)carbonamido-.alpha.-ph enylacetyl, and 2-thienylacetyl).

REFERENCES:
patent: 3974154 (1976-08-01), Nayler et al.
patent: 4013653 (1977-03-01), Wolfe
Chemical Abstracts, vol. 81, Abst. No. 37560f (1974) (Abst. of Christensen et al., Ger. Offen. 2,355,209).

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