Cephalosporanic acid derivatives

Details Cephalosporanic acid derivatives Cephalosporanic acid derivatives

1980-04-30

1982-06-22

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 544028, C07D50136

Patent

active

043363750

ABSTRACT:
7-acetamidocephalosporins are disclosed herein which are substituted at position 3 of the cephalosporin nucleus with the group ##STR1## wherein R.sub.2 is selected from the group hydrogen, amino, C.sub.1 to C.sub.6 alkylamino and di-C.sub.1 to C.sub.6 alkylamino and R.sub.3, R.sub.4 and R.sub.5 are the same or different and are selected from the group hydrogen, hydroxy, C.sub.1 to C.sub.6 alkyl, C.sub.1 to C.sub.6 alkoxy, trifluoromethyl, substituted phenyl heterocyclic aryl and R.sub.3 and R.sub.4 or R.sub.4 and R.sub.5 taken together are the moiety --CH.sub.2 (CH.sub.2).sub.2 CH.sub.2 --.

REFERENCES:
patent: 4113944 (1978-09-01), Kai et al.
patent: 4179502 (1979-12-01), Numata et al.

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