Cephaloporins and homologues, preparations and pharmaceutical co

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540222, 540300, 540301, A61K 31545, A61K 31435, C07D50120, C07D46300

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active

060203293

ABSTRACT:
.beta.-Lactam antibiotics of formula (I) or a salt thereof, wherein R.sup.1 is hydrogen, methoxy or formamido; R.sup.2 is an acy group; CO.sub.2 R.sup.3 is a carboxy group or a carboxylate anion, or R.sup.3 is a readily removable carboxy protecting group; R.sup.4 represents up to four substituents; X is S, SO, SO.sub.2, O or CH.sub.2 ; m is 1 or 2; and n is 0, useful in the treatment of bacterial infec ##STR1##

REFERENCES:
patent: 3939157 (1976-02-01), Nayler et al.
patent: 3959267 (1976-05-01), Nayler et al.
patent: 3962223 (1976-06-01), Martel et al.
patent: 3975383 (1976-08-01), Nayler et al.
patent: 5246926 (1993-09-01), Bateson et al.
"Drugs of the Future", vol. 14, No. 1,1989, pp. 73-74.
"Drugs of the Future", vol. 13, No. 1, 1988, pp. 16-19.

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