Cephadroxil monohydrate

Details Cephadroxil monohydrate Cephadroxil monohydrate

1982-03-16

1985-03-12

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50122, C07D50112

Patent

active

045046573

ABSTRACT:
A novel crystalline monohydrate of 7-[D-.alpha.-amino-.alpha.-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4 -carboxylic acid is prepared and found to be a stable useful form of the cephalosporin antibiotic especially advantageous for pharmaceutical formulations.

REFERENCES:
patent: 3489752 (1970-01-01), Crast, Jr.
patent: 3655656 (1972-04-01), Van Heyningen
patent: 3781282 (1973-12-01), Garbrecht
patent: 3957773 (1976-05-01), Burton
patent: 3985741 (1976-10-01), Crast, Jr.
patent: 4091215 (1978-05-01), Bouzard
patent: 4160863 (1979-07-01), Bouzard et al.
patent: 4162314 (1979-07-01), Gottschlich
Dunn et al., The Journal of Antibiotics, 29: 65-80, (Jan. 1976).

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