Centrosome-associated protein and applications thereof

Details Centrosome-associated protein and applications thereof Centrosome-associated protein and applications thereof

2008-07-22

2008-07-22

Mondesi, Robert B (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

Reexamination Certificate

active

10540493

ABSTRACT:
The invention relates to a novel centrosome-associated protein, to the polynucleotide coding for the aforementioned protein and to the applications of said protein and polynucleotide. The overexpression of the inventive protein disrupts the mitotic spindle assembly and leads to aberrant and abortive mitoses.

REFERENCES:
patent: WO 00/73801 (2000-12-01), None
patent: WO 02/070539 (2002-12-01), None
STIC Sequence alignment, OM protein—protein search, using sw model Run on: Apr. 19, 2007, pp. 1-3.
XP002252293, “Homo sapiensBAC clone RP11-27G13 from 4, complete sequence”, Waterstone R.H., 1998.
XP-002288171, “Homo sapienscDNA: FLJ21159 fis, clone CAS09969”, Sugano S. et al., 1997.
XP-002288169, “Centrosomes and Cancer: lessons from a TACC,” Jordan W. Raff, 1998.
XP-002288170, “Centromere proteins and chromosome inheritance: a complex affair”, Kenneth W. Dobie et al., 2000.
XP-002307713, “Mus musculusadult male pituitary gland cDNA,”, 1998.
XP-002307714, “Mus musculusRiken cDNA 5330427D05 gne, mRNA (cDNA clone IMAGE: 30254438) partial cds”, 1999.

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