Centrifuge tube sequential fractionator

Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition

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422 72, 422100, 233 1R, 210 94, 210515, G01N 102

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active

041817001

ABSTRACT:
A device for the sequential fractionation of the contents of a centrifuge tube containing centrifugally separated contents utilizing a syringe-like apparatus. The present invention utilizes removable syringe tips that are mounted on a chamber housing for extraction and retention of a precise volume of centrifuged fluid from the centrifuge tube. The syringe-like apparatus is mounted to a frame in such a manner that the chamber housing is movable relative to the plunger or piston to permit precise movement of the chamber housing with the removable syringe tip into the centrifuge tube for delicate and precise removal of the desired fraction of the fluid. The syringe tips are removed with each fraction that is collected from the contents in the centrifuge tube and can be placed in a storage rack for subsequent analysis.

REFERENCES:
patent: 4003834 (1977-01-01), Coombs
Lammers, "Fractionation of Suspended and Colloidal Particles in Natural Waters", Report K-7749 (1968), Oak Ridge Gaseous Diffusion Plant, Tennessee.
Hill et al., "Apparatus for Collecting Fractions from Density Differential Interfaces and Its Use in Grav. Meas. of Total Myelin", Clin. Chem., vol. 16, No. 3 (1970), pp. 171-172.
Abdel-Latif, "Methods in Neurochemistry", vol. 5, p. 147 (1973).
Germain, "A Single Apparatus for Retrieving Density Gradients by Surface Tension", Anal. Biochem., vol. 57, pp. 89-92 (1974).
Rothschild, "Acid Phosphates in Amoeba Cell Fractions", C. R. Trav. Lab. Carlsberg, vol. 35, p. 457 (1967).
Bishop et al., "Red Cells in Density Gradients", Journal of Physics, vol. 67, p. 197 (1966).

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