Chemistry: physical processes
Patent
1976-08-16
1978-02-28
Krizmanich, George H.
Chemistry: physical processes
233 19R, 233 21, 233 27, 233 46, B04B 1102, B04B 1506
Patent
active
040761690
ABSTRACT:
A centrifuge device and method are provided for separating and/or washing finely-divided solid particulate material suspended in a liquid. The invention is especially useful in so treating blood. The centrifuge forms a dense suspension of blood cells in a plurality of blood cells receiving means evenly spaced about the periphery of a rotatable enclosure. The receiving means have converging walls which at their juncture form a locus of maximum centrifugal force. Wash liquid is passed through the dense suspension of blood cells counter to the direction of the centrifugal force by entry into the blood cell receiving means at the locus of maximum centrifugal force. Independent conduits connect the locus of maximum centrifugal force through an injector to a supply for the wash liquid and, after fully resuspending the blood cells in a suitable resuspending liquid, the resuspended cells exit from the centrifuge via the independent conduits and injector, which have also therefore been washed by the wash liquid. Thus recontamination is avoided. A unitary disposable structure including the enclosure, blood cell receiving means, conduits and injector is also provided.
REFERENCES:
patent: 3326458 (1967-06-01), Meryman et al
patent: 3347454 (1967-10-01), Bellamy et al.
patent: 3561672 (1971-02-01), Schlutz et al.
patent: 3748101 (1973-07-01), Jones et al.
patent: 3843046 (1974-10-01), Joyce
patent: 3987961 (1976-10-01), Sinn et al.
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