Centrifuge bag-holding device with clamp assembly and uses there

Details Centrifuge bag-holding device with clamp assembly and uses there Centrifuge bag-holding device with clamp assembly and uses there

1998-07-13

2000-02-01

Cooley, Charles E.

Imperforate bowl: centrifugal separators

Including plurality of miniature bowls distrubuted about...

Comprising flexible bowls embraced by pockets provided...

494 37, B04B 502

Patent

active

060197161

ABSTRACT:
A device is provided for use in a centrifuge to separate or isolate material (such as pelleted cells, particulates, aggregates, compounds, blood components, and the like) from the liquid in which they are suspended while limiting or preventing loss of any of the resulting separated or pelleted material during further manipulations. The device can be inserted into a standard centrifugation bucket in a centrifuge and holds a flexible centrifuge bag. The device includes at least one damp assembly, which includes a partition that is maintained in an open position during centrifugation and in a closed position at unit gravity, thus isolating separated or pelleted material at the bottom of the flexible bag in the device after centrifugation and preventing the isolated material from being disturbed during liquid changes and other manipulations. The invention also encompasses a method for isolating material in a centrifuge bag following centrifugation utilizing the flexible bag-holding device described herein, as well as a flexible bag to be used with the device.

REFERENCES:
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patent: 3559880 (1971-02-01), Naito et al.
patent: 4146172 (1979-03-01), Cullis et al.
patent: 4195766 (1980-04-01), Lamadrid et al.
patent: 4266717 (1981-05-01), Jennings et al.
patent: 4582606 (1986-04-01), McCarty
patent: 4617009 (1986-10-01), Ohlin et al.
patent: 4909949 (1990-03-01), Harmony et al.
patent: 5224921 (1993-07-01), Dennehey et al.

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