Centrifugal separation apparatus and method for separating...

Imperforate bowl: centrifugal separators – Process

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C494S045000

Reexamination Certificate

active

07549956

ABSTRACT:
An apparatus and method are provided for separating components of a fluid or particles. A separation vessel having a barrier dam is provided to initially separate an intermediate density components of a fluid, and a fluid chamber is provided to further separate these intermediate density components by forming an elutriative field or saturated fluidized particle bed. The separation vessel includes a shield for limiting flow into the fluid chamber of relatively high density substances, such as red blood cells. The separation vessel also includes a trap dam with a smooth, gradually sloped downstream section for reducing mixing of substances. Structure is also provided for adding additional plasma to platelets and plasma flowing from the fluid chamber. The system reduces clumping of platelets by limiting contact between the platelets and walls of the separation vessel.

REFERENCES:
patent: 1684870 (1928-09-01), Lewis
patent: 2616619 (1952-11-01), MacLeod
patent: 2878995 (1959-03-01), Dega
patent: 3771715 (1973-11-01), Baram
patent: 3823869 (1974-07-01), Loison
patent: 3825175 (1974-07-01), Sartory
patent: 4007871 (1977-02-01), Jones et al.
patent: 4010894 (1977-03-01), Kellogg et al.
patent: 4059967 (1977-11-01), Rowe et al.
patent: 4091989 (1978-05-01), Schlutz
patent: 4094461 (1978-06-01), Kellogg et al.
patent: 4146172 (1979-03-01), Cullis et al.
patent: 4187979 (1980-02-01), Cullis et al.
patent: 4198972 (1980-04-01), Herb
patent: 4268393 (1981-05-01), Persidsky et al.
patent: 4316576 (1982-02-01), Cullis et al.
patent: 4322298 (1982-03-01), Persidsky
patent: 4350283 (1982-09-01), Leonian
patent: 4356958 (1982-11-01), Kolobow et al.
patent: 4386730 (1983-06-01), Mulzet
patent: 4387848 (1983-06-01), Kellogg et al.
patent: 4413771 (1983-11-01), Rohde et al.
patent: 4413772 (1983-11-01), Rohde et al.
patent: 4416654 (1983-11-01), Schoendorfer et al.
patent: 4419089 (1983-12-01), Kolobow et al.
patent: 4421503 (1983-12-01), Latham, Jr. et al.
patent: 4425112 (1984-01-01), Ito
patent: 4430072 (1984-02-01), Kellogg et al.
patent: 4447221 (1984-05-01), Mulzet
patent: 4464167 (1984-08-01), Schoendorfer et al.
patent: 4610846 (1986-09-01), Martin
patent: 4647279 (1987-03-01), Mulzet et al.
patent: 4675117 (1987-06-01), Neumann et al.
patent: 4680025 (1987-07-01), Kruger et al.
patent: 4701267 (1987-10-01), Watanabe et al.
patent: 4708710 (1987-11-01), Dunn, Jr.
patent: 4708712 (1987-11-01), Mulzet
patent: 4798579 (1989-01-01), Penhasi
patent: 4808151 (1989-02-01), Dunn, Jr. et al.
patent: 4834890 (1989-05-01), Brown et al.
patent: 4846974 (1989-07-01), Kelley et al.
patent: 4851126 (1989-07-01), Schoendorfer
patent: 4885137 (1989-12-01), Lork
patent: 4911833 (1990-03-01), Schoendorfer et al.
patent: 4915847 (1990-04-01), Dillon et al.
patent: 4933291 (1990-06-01), Daiss et al.
patent: 4934995 (1990-06-01), Cullis
patent: 4936820 (1990-06-01), Dennehey et al.
patent: 4936998 (1990-06-01), Nishimura et al.
patent: 4939081 (1990-07-01), Figdor et al.
patent: 4939087 (1990-07-01), Van Wie et al.
patent: 5006103 (1991-04-01), Bacehowski et al.
patent: 5076911 (1991-12-01), Brown et al.
patent: 5078671 (1992-01-01), Dennehey et al.
patent: 5089146 (1992-02-01), Carmen et al.
patent: 5100564 (1992-03-01), Pall et al.
patent: 5160310 (1992-11-01), Yhland
patent: 5203999 (1993-04-01), Hugues
patent: 5213970 (1993-05-01), Lopez-Berestein et al.
patent: 5217427 (1993-06-01), Cullis
patent: 5224921 (1993-07-01), Dennehey et al.
patent: 5229012 (1993-07-01), Pall et al.
patent: 5260598 (1993-11-01), Brass et al.
patent: 5282982 (1994-02-01), Wells
patent: 5298171 (1994-03-01), Biesel
patent: 5316666 (1994-05-01), Brown et al.
patent: 5316667 (1994-05-01), Brown et al.
patent: 5360542 (1994-11-01), Williamson, IV et al.
patent: 5362291 (1994-11-01), Williamson, IV et al.
patent: 5370802 (1994-12-01), Brown
patent: 5397479 (1995-03-01), Kass et al.
patent: 5409813 (1995-04-01), Schwartz
patent: 5437624 (1995-08-01), Langley
patent: 5494592 (1996-02-01), Latham, Jr. et al.
patent: 5501795 (1996-03-01), Pall et al.
patent: 5529691 (1996-06-01), Brown
patent: 5547591 (1996-08-01), Hagihara et al.
patent: 5549834 (1996-08-01), Brown
patent: 5571068 (1996-11-01), Bacehowski et al.
patent: 5580465 (1996-12-01), Pall et al.
patent: 5587070 (1996-12-01), Pall et al.
patent: 5607830 (1997-03-01), Biesel et al.
patent: 5628915 (1997-05-01), Brown et al.
patent: 5641414 (1997-06-01), Brown
patent: 5656163 (1997-08-01), Brown
patent: 5674173 (1997-10-01), Hlavinka et al.
patent: 5690835 (1997-11-01), Brown
patent: 5702357 (1997-12-01), Bainbridge et al.
patent: 5704888 (1998-01-01), Hlavinka et al.
patent: 5704889 (1998-01-01), Hlavinka et al.
patent: 5720716 (1998-02-01), Blakeslee et al.
patent: 5722926 (1998-03-01), Hlavinka et al.
patent: 5792038 (1998-08-01), Hlavinka et al.
patent: 5792372 (1998-08-01), Brown et al.
patent: 5858251 (1999-01-01), Borchardt et al.
patent: 5904645 (1999-05-01), Hlavinka et al.
patent: 5906570 (1999-05-01), Langley et al.
patent: 5913768 (1999-06-01), Langley et al.
patent: 5939319 (1999-08-01), Hlavinka et al.
patent: 5951877 (1999-09-01), Langley et al.
patent: 5954626 (1999-09-01), Hlavinka
patent: 6053856 (2000-04-01), Hlavinka
patent: 6071422 (2000-06-01), Hlavinka et al.
patent: 6334842 (2002-01-01), Hlavinka et al.
patent: 6354986 (2002-03-01), Hlavinka et al.
patent: 26 58 926 (1978-06-01), None
patent: 28 21 055 (1979-04-01), None
patent: 37 00 122 (1988-07-01), None
patent: 0 057 907 (1982-08-01), None
patent: 0 363 120 (1990-04-01), None
patent: 0 406 485 (1991-01-01), None
patent: 0 408 462 (1991-01-01), None
patent: 0 419 346 (1991-03-01), None
patent: WO 94/02157 (1994-02-01), None
patent: WO 94/27698 (1994-12-01), None
patent: WO 96/32198 (1996-10-01), None
patent: WO 96/33023 (1996-10-01), None
patent: WO 96/40402 (1996-12-01), None
patent: WO 96/40403 (1996-12-01), None
patent: WO 97/30748 (1997-08-01), None
patent: WO 97/43045 (1997-11-01), None
patent: WO 98/50163 (1998-11-01), None
Maxim D. Persidsky et al., Separation of Platelet-rich Plasma by Modified Centrifugal Elutriation; Journal of Clinical Apheresis 1:18-24 (1982).
John F. Jemionek et al., Special Techniques for the Separation of Hemopoietic Cells, Current Methodology in Experimental Hematology, 1984, pp. 12-16.
J. Freedman et al., White Cell Depletion of Red Cell and Pooled Random-Donor Platelet Concentrates by Filtration and Residual Lymphocyte Subset Analysis, Transfusion, 1991, vol. 31, No. 5, pp. 433-440.
Nancy M. Heddle et al., The Role of the Plasma from Platelet Concentrates in Transfusion Reactions, The New England Journal of Medicine, vol. 331, No. 10, Sep. 8, 1994, pp. 625-628, 670 and 671.
A. Bruil et al., Asymmetric Membrane Filters for the Removal of Leukocytes From Blood, Journal of Biomed. Materials Research, vol. 25, 1459-1480, 1991.
Sunny Dzik, Leukodepletion Blood Filters: Filter Design and Mechanisms of Leukocyte Removal, Transfusion Medicine Reviews, vol. VII, No. 2, Apr. 1993, pp. 65-77.
Bernard J. Van Wie et al., The Effect of Hematocrit and Recycle on Cell Separations, Plasma Ther. Transfus. Technol. 1986; 7:373-388.
P.D. Drumheller et al., The Effects of RPM and Recycle on Separation Efficiency in a Clinical Blood Cell Centrifuge, Journal of Biomechanical Engineering, Nov. 1987, vol. 109, pp. 324-329.
R.J. Oxford et al., Interface Dynamics in a Centrifugal Cell Separator, Transfusion, Nov.-Dec. 1988, vol. 28, Nov. 6, pp. 588-592.
A. Tulp et al., A Separation Chamber to Sort Cells and Cell Organelles by Weak Physical Forces, V.A. Sector-Shaped Chamber and Its Application to the Separation of Peripheral Blood Cells, Journal of Immunological Methods 69 (1984), pp. 281-295.
Carl G. Figdor et al., Theory and Practice of Centrifugal Elutriation (CE) Factors Influencing the Separation of Human Blood Cells, Cell Biophysics 5, 105-118 (1983).
P.E. Lindahl, On Counter Streaming Centrifugation in the Separation of Cells and Cell Fragments (1956), pp. 411-415.
C. Almici et al., Counterflow Centrifugal Elutriation: Present and Future, Bone Marrow Transplantation 1993, 12:105-108.
Richar

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Centrifugal separation apparatus and method for separating... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Centrifugal separation apparatus and method for separating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Centrifugal separation apparatus and method for separating... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4081574

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.