Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is particulate and the particles are of...
Patent
1985-05-14
1988-01-19
Warden, Robert J.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is particulate and the particles are of...
436517, 436518, 436524, 436531, 436534, 436805, G01N 33557, G01N 33543, G01N 33551, G01N 33546
Patent
active
047204656
ABSTRACT:
A sample is mixed with a reagent containing stably suspended particles coated with a binding pair member complementary to or competitive with the target binding pair member. A centrifugal force applied during reaction is sufficient to change the concentration of particles at a locus relative to overall particle concentration. Light transmission or scattering is measured kinetically at the locus, especially in a microcentrifugal analyzer.
REFERENCES:
patent: 4003988 (1977-01-01), Hoff et al.
patent: 4202665 (1980-05-01), Wenz et al.
patent: 4205954 (1980-06-01), Babson
patent: 4305721 (1981-12-01), Bernstein
Wenz, B. et al., Clin. Chem., 25, No. 9:1613-1616 (1979).
Dummel Robert J.
Huang Pih-Kuei C.
Jensen Mona D.
Lentrichia Brian B.
Yeung Kwok K.
Doernberg Alan M.
Fisher Scientific Company
Spiegel Jack
Warden Robert J.
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