Centrifugal counter-current distribution chromatography

Details Centrifugal counter-current distribution chromatography Centrifugal counter-current distribution chromatography

1989-08-29

1990-11-06

Therkorn, Ernest G.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210657, 422 70, 436161, B01D 1508

Patent

active

049684280

ABSTRACT:
A cassette for use in a centrifugal counter-current distribution chromatographic apparatus which comprises a motor-driven rotor supported for rotation about a shaft having at least one pocket defined therein, and at least one cassette having a tortuous separation passage defined therein with the opposite ends adapted to be connected respectively to a source of fluid samples and the outside, the fluid samples being continuously supplied to the separation passage while the rotor is driven in one direction at high speed to effect the counter-current distribution. The cassette comprises at least one flat plate member having defined therein a plurality of slots and a corresponding number of narrow grooves alternating with the slots, each of the narrow grooves being continued at one end to one slot and at the other end to the next adjacent slot, sealing plates disposed on respective side faces of the flat plate member, and metallic side plates clamped together with the flat plate member and the sealing plates disposed therebetween. The slots and narrow grooves are so defined in the flat plate member that, when the cassette is mounted on the rotor, they can be oriented radially of the rotor.

REFERENCES:
patent: 4051025 (1977-09-01), Ito
patent: 4324661 (1982-04-01), Ito
patent: 4551251 (1985-11-01), Kolobow
patent: 4632762 (1986-12-01), Ramsland

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