Cellulose binding domain proteins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530395, 530402, C07K 1400, C07K 113

Patent

active

058378146

ABSTRACT:
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

REFERENCES:
patent: 5137819 (1992-08-01), Kilburn et al.
patent: 5202247 (1993-04-01), Kilburn et al.
patent: 5496934 (1996-03-01), Shoseyov et al.
Lewin. 1988. Science 237: 1570.
Reeck et al. 1987. Cell: 50: 667.
Bowie et al. 1990. Science 247: 1306-1310.
Foong et al., 1991, "Nucleotide Sequence and Characteristics of Endoglucae Gene engB from Clostridium cellulovorans, "Journal of General Microbiology 137:1729-1736.
Shoseyov et al., 1991, "Nucleotide Sequence of Clostridium cellulovorans Gene Homologous to Cyclic-AMP Dependent Kinase," Nucleic Acids Res. 19:1710.
Shoseyov et al., 1990, "Cloning of 170 dKa Clostridium cellulovorans Cellulase Subunit: An Essential Protein for the Degradation of Crystalline Cellulose," Abstracts of the Annual Meeting of the American Society for Microbiology O-24.
Shoseyov et al., 1990, "Cloning of Clostridium Cellulovorans Endo-1,4-.beta.-Glucanase Genes," Biochem. Biophys. Res. Commun. 169(2):667-672.
Nilsson et al. 1985, "Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors," EMBO J. 4(4):1075-1080.
MacKay et al., 1986, "Structure of a Bacillus subtilis endo-.beta.-1,4-glucanase gene," Nucleic Acids Research , vol. 14, No. 22, pp. 9159-9170.
Mehra et al., 1986, "Efficient mapping of protein antigenic determinants," Proc. Natl. Acad. Sci. USA 83:7013-7017.
Shinnick, Thomas M., 1987, "The 65-Kilodalton Antigen of Mycobacterium tuberculosis, " J. of Bacteriology169(3):1080-1088.
Cabib, Enrico, 1988,"Chitinase from Serratia marcescens," Methods in Enzymology 161:460-462.
Hemmingsen et al., 1988, "Homologous plant and bacterial proteins chaperone oligomeric protein assembly," Nature 333:330-334.
Shinnick et al., 1988, "The Mycobacterium tuberculosis 65-Kilodalton Antigen Is a Heat Shock Protein Which Corresponds to Common Antigen and to the Escherichia coli GroEL Protein," Infection and Immunity 56(2):446-451.
van Eden et al., 1988, "Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis," Nature 331:171-173.
Greenwood et al., 1989, "Fusion to an endoglucanase allows alkaline phosphatase to bind to cellulose," EBS Letters 244(1):127-131.
Jindal et al., 1989, "Primary Structure of a Human Mitochondrial Protein Homologous to the Bacterial and Plant Chaperonins and to the 65-Kilodalton Mycobacterial Antigen," Mol. and Cell. Biol. 9(5):2279-2283.
Picketts et al., 1989, "Molecular Cloning of a Chinese Hamster Mitochondrial Protein Related to the Chaperonin Family of Bacterial and Plant Proteins," J. Biol. Chem. 264:12001-12008.
Saul et al., 1989, "Nucleotide sequence of a gene from Caldocellum saccharolyticum encoding for exocellulase and endocellulase activity," Nucleic Acids Research, vol. 17, No. 1, pp. 439.
Billingham et al., 1990, "A Mycobacterial 65-kD Heat Shock Protein Induces Antigen-Specific Suppression of Adjuvant Arthritis, But Is Not Itself Arthritogenic," J. Exp. Med. 171:339-334.
Elias et al., 1990, "Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein," Proc. Natl. Acad. Sci. USA 87:1576-1580.
Ellis, John, 1990, "The Molecular chaperone concept," Seminars in Cell Biology 1:1-9.
Klyosov, Anatole A., 1990, "Trends in Biochemistry and Enzymology of Cellulose Degradation," Biochemistry 29(47):10577-10585.
Shoseyov et al., 1990, "Essential 170-kDa subunit for degradation of crystalline cellulose by Clostridium cellulovorans cellulase," Proc. Natl. Acad. Sci. USA 87:2192-2195.
Shoseyov et al., 1990, "Immobilized Endo-.beta.-glucosidase Enriches Flavor of Wine and Passion Fruit Juice," JAFCU 38(6):1387-1390.
Venner et al., 1990, Nucleotide sequence of rat hsp60 (chaperonin, GroEL homolog) cDNA, Nuc. Acids Res. 18(17):5309.
Din et al., 1991, "Non-Hydrolytic Disruption of Cellulose Fibres by the Binding Domain of a Bacterial Cellulase," Bio/Technology 9:1096-1099.
Hermann et al., 1991, "Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells," Eur. J. Immunol. 21:2139-2143.
van Eden, Willem, 1991, "Heat-Shock Proteins as Immunogenic Bacterial Antigens with the Potential to Induce and Regulate Autoimmune Arthritis," Immunological Reviews 121:5-28.
Hansen et al., 1992, "celA from Bacillus lautus PL236 Encodes a Novel Cellulose-Binding Endo-.beta.-1,4-Glucanase," Journal of Bacteriology, vol. 174, No. 11, pp. 3522-3531.
Shoseyov et al., 1992, "Primary sequence analysis of Clostridium cellulovorans cellulose binding protein A," Proc. Natl. Acad. Sci. USA 89:3483-3487.
Gerngross et al., 1993, "Sequencing of a Clostridium thermocellum gene (cipA) encoding the cellulosomal S.sub.L -protein reveals an unusual degree of internal homology," Molecular Biology, vol. 8, No. 2, pp. 325-334.
Hazlewood et al., 1993, Gene sequence and properties of Cell, a family E endoglucanase from Clostridium thermocellum, Journal of General Microbiology, vol. 139:pp. 307-316.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cellulose binding domain proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cellulose binding domain proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cellulose binding domain proteins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-885410

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.