Combinatorial chemistry technology: method – library – apparatus – Method specially adapted for identifying a library member – Identifying a library member by means of a tag – label – or...
Reexamination Certificate
2006-08-30
2010-02-23
Wessendorf, T. D. (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method specially adapted for identifying a library member
Identifying a library member by means of a tag, label, or...
C506S001000, C506S002000, C506S003000, C506S014000, C506S018000, C435S007200, C435S007370, C435S007400, C435S004000
Reexamination Certificate
active
07666817
ABSTRACT:
The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme.
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Boulware Kevin T.
Daugherty Patrick Sean
Bozicevic Field & Francis LLP
Rubin Michael B.
The Regents of the University of California
Wessendorf T. D.
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