Cellular fibronectin: polypeptides, anti-polypeptide antibodies

Details Cellular fibronectin: polypeptides, anti-polypeptide antibodies Cellular fibronectin: polypeptides, anti-polypeptide antibodies

1986-04-15

1990-12-25

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436501, 436547, 436548, 436 87, 530395, G01N 3353, G01N 33566, G01N 3300

Patent

active

049802798

ABSTRACT:
A synthetic polypeptide is disclosed that substantially corresponds in sequence to a portion of the amino acid residue sequence of the 90 amino acid residue extra type III domain of human cellular fibronectin from about position 36 to about position 60 from the amino-terminus. The polypeptide contains about 10 to about 25 amino acid residues. Also disclosed are antibodies and methods of using both the polypeptide and antibodies.

REFERENCES:
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Schoen, R. C. et al., Hybridoma, vol. 1, No. 2, pp. 99-108, (1982).
Lerner, R. A., Nature, vol. 299, pp. 592-596 (1982).
Paul et al., J. Biol. Chem., 261:12258-12265 (1986).
Berzofsky, Science, 229:932-940 (1985).
Barlow et al., Nature, 322:747-748 (1986).
Keen et al., Mol. Biol. Med., 2:15-27 (1984).
White et al., Principles of Biochemistry, Sixth Ed., McGraw-Hill Book Co., New York (1978) p. 140.
Borsi et al., J. Cell. Biol., 104:595-600 (1987).

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