Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2005-01-29
2009-12-15
Borin, Michael (Department: 1631)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C435S007100, C436S510000, C600S300000, C600S301000
Reexamination Certificate
active
07634360
ABSTRACT:
The present invention relates to methods for the diagnosis and evaluation of stroke and stroke sub-type. A variety of bio-markers are disclosed for assembling a panel for such diagnosis and evaluation. Methods are disclosed for selecting markers and correlating their combined levels with a clinical outcome of interest. In various aspects: the invention provides methods for early detection and differentiation of stroke subtypes, for determining the prognosis of a patient presenting with stroke symptoms, and identifying a patient at risk for hemorrhagic transformation after thrombolyic therapy. Methods are disclosed that provide rapid, sensitive and specific assays to greatly increase the number of patients that can receive beneficial stroke treatment and therapy, and reduce the costs associated with incorrect stroke diagnosis.
REFERENCES:
patent: 5079171 (1992-01-01), Senyei et al.
patent: 2003/0100010 (2003-05-01), Jackowski et al.
Hegele et al. Database Caplus, DN: 141:377907, 2004.
Castellanos Mar
Castillo José
Davalos Antoni
Diamond Cornelius Allen
Borin Michael
Fuess & Davidenas
Prediction Sciences, LL
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