Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-06-07
1998-06-02
Chambers, Jasemine C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4353201, 435 691, 4351723, 935 56, 935 71, 935 65, 935 62, 536 245, C07H 2100, C07H 2104, C12N 1563, C12N 1509
Patent
active
057597820
ABSTRACT:
The cDNA and amino acid sequences for a cellular apoptosis susceptibility (CAS) protein are used to detect expression and amplification of the CAS gene in normal and cancer cells. An antisense CAS gene sequence introduced into living cells inhibits CAS protein activity and thus prevents or inhibits apoptosis in the cells.
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Brinkmann Ulrich
Pastan Ira
Chambers Jasemine C.
Hauda Karen M.
The United States of America
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