Optics: measuring and testing – Sample – specimen – or standard holder or support
Reexamination Certificate
2010-05-12
2010-11-16
Nguyen, Sang (Department: 2886)
Optics: measuring and testing
Sample, specimen, or standard holder or support
C356S246000, C422S082110, C435S007100, C435S288300
Reexamination Certificate
active
07834998
ABSTRACT:
The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
REFERENCES:
patent: 3486829 (1969-12-01), Wilks, Jr.
patent: 5677196 (1997-10-01), Herron et al.
patent: 5747349 (1998-05-01), van den Engh et al.
patent: 5814565 (1998-09-01), Reichert et al.
patent: 5959728 (1999-09-01), Nishimoto et al.
patent: 6017434 (2000-01-01), Simpson et al.
patent: 6188474 (2001-02-01), Dussault et al.
patent: 6376231 (2002-04-01), Enomoto et al.
patent: 6457361 (2002-10-01), Takeuchi et al.
patent: 6485905 (2002-11-01), Hefti
patent: 6498353 (2002-12-01), Nagle et al.
patent: 6600558 (2003-07-01), Ueno et al.
patent: 6716629 (2004-04-01), Hess et al.
patent: 7306941 (2007-12-01), Fujimura et al.
patent: 7569354 (2009-08-01), Okano et al.
patent: 2002/0176804 (2002-11-01), Strand et al.
patent: 2003/0162283 (2003-08-01), Kuno et al.
patent: 2005/0014246 (2005-01-01), Kohara et al.
Toru Fujimura et al., “Silicon-Based Optical Thin-Film Biosensor Array for Real-Time Measurements of Biomolecular Interaction”, Japanese Journal of Applied Physics, 2005, vol. 44, No. 4B, pp. 2849-2853.
Torbjorn Sandstrom et al., “Visual Detection of Organic Monomolecular Films by Interference Colors”, Applied Optics, vol. 24, No. 4, Feb. 1985, pp. 472-479.
M. Harris et al., “The Relationship Between Optical Inhomogeneity and Film Structure”, Thin Solid Films, vol. 57 (1979), pp. 173-178.
Fujimura Toru
Ide Tatsuro
Kuwabara Kosuke
A. Marquez, Esq. Juan Carlos
Hitachi , Ltd.
Nguyen Sang
Stites & Harbison PLLC
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