Cell-type specific transcription factor

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4351723, 4352523, 435325, 536 235, 536 243, 536 2431, C12P 2102, C12N 121, C12N 510, C12N 1512

Patent

active

057100250

ABSTRACT:
The invention provides methods and compositions relating to human tata-binding protein associated factor 105 (hTAF.sub.II 105) and related nucleic acids. The proteins may be produced recombinantly from transformed host cells from the disclosed hTAF.sub.II 105 encoding nucleic acids or purified from human cells. The invention provides isolated hTAF.sub.II 105 hybridization probes and primers capable of specifically hybridizing with the disclosed hTAF.sub.II 105 gene, hTAF.sub.II 105-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.

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