Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2008-12-05
2011-10-04
Whiteman, Brian (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S024500
Reexamination Certificate
active
08030290
ABSTRACT:
The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer.
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patent: 2007/143086 (2007-12-01), None
McNamara et al., “Cell type-specific delivery of siRNAs with aptamer siRNA chimeras,” Nature Biotechnology 24(8): 1005-1015 (2006).
Third Party Submission dated Aug. 10, 2009, John J. Rossi et al., U.S. Appl. No. 12/328,994, 5 pages.
Makobetsa Khati et al., “Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers,” Journal of Virology, Dec. 2003, vol. 77, No. 23, pp. 12692-12698, Copyright 2003, American Society for Microbiology, 7 pages.
Rossi John J.
Zhou Jiehua
City of Hope
Rothwell, Figg Ernst & Manbeck, PC
Whiteman Brian
LandOfFree
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