Cell/tissue culture apparatus

Details Cell/tissue culture apparatus Cell/tissue culture apparatus

2008-07-15

2008-07-15

Beisner, William H (Department: 1797)

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

C435S293100, C435S302100

Reexamination Certificate

active

10475183

ABSTRACT:
The invention provides a cell/tissue culture apparatus capable of applying an optional physical stimulation to a material to be cultivated serving as a cell or tissue to be cultivated and of protecting the material to be cultivated from contamination of various bacteria and so forth. The cell/tissue culture apparatus comprises a chamber (culture chamber8) for accommodating the material to be cultivated (matrix10) therein and receiving a culture fluid (18), a disc (24) rotatably installed in the chamber for applying a physical stimulation to the material to be cultivated by way of the culture fluid (18) when it is rotated, and rotary driving means (external rotation body32and motor40) for applying a rotating force to the disc from an outside of the chamber in a state where it does not contact the disc, and it can apply an optional physical stimulation to the material to be cultivated serving as the cell or tissue to be cultivated, protecting the material to be cultivated from contamination of bacteria and so forth.

REFERENCES:
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patent: 6121042 (2000-09-01), Peterson et al.
patent: 3714708 (1988-02-01), None
patent: 03007575 (1991-01-01), None
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patent: WO-98/225573 (1998-05-01), None
patent: WO-9822573 (1998-05-01), None
Blackman et al.‘In Vitro Cell Shearing Device to Investigate the Dynamic Response of Cells in a Controlled Hydrodynamic Environment.’ Annals of Biomedical Engineering. vol. 28 (2000), pp. 363-372.
International Search Report (Apr. 2002).
Supplementary European search report issued in corresponding European Application No. 02700699.8 Mar. 27, 2007.

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