Cell surface modification using a novel glycoproteinase of paste

Details Cell surface modification using a novel glycoproteinase of paste Cell surface modification using a novel glycoproteinase of paste

1986-10-06

1990-03-06

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435822, C12N 952, C12R 101

Patent

active

049065718

ABSTRACT:
A glycoproteinase derived from the culture of Pasteurella haemolytica cleaves carbohydrate antigen markers from glycoproteins forming an integral part of plant and mammal cell membrane without general enzyme digestion of other cell protein. The glycoproteinase is separated from the media containing nutrients which induce Pasteurella haemolytica to produce the glycoproteinase released into the media.

REFERENCES:
patent: 4390629 (1983-06-01), Goldberg et al.
Otulakowsky, G. L. et al, Infect. Immun., 42:64-70, (1983) "Proteolysis of Sialoglycoprotein by Pasteurella haemolytica Cytoxic Culture Supernatant".

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